What is Oxycodone ?
Oxycodone is a moderately priced drug used to treat moderate to severe pain. This drug is slightly more popular than comparable drugs. It is available in both generic and brand versions.Take this medication by mouth with water. Take it at the same time each day as directed on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Keep drinking unless your team tells you to stop.
Some brands of this drug, such as B. Oxaydo, have special instructions. Ask your caregiver or pharmacist if these instructions apply to you: Do not cut, crush, or chew this medication. Do not wet, soak or lick the tablet before taking it.
Your pharmacist will provide you with a special MedGuide with each prescription and refill. Read this information carefully each time.
Talk to your childcare team about using this medicine in children. Special care may be required.
Some brands of this drug, such as B. Oxaydo, have special instructions. Ask your caregiver or pharmacist if these instructions apply to you: Do not cut, crush, or chew this medication. Do not wet, soak or lick the tablet before taking it.
Your pharmacist will provide you with a special MedGuide with each prescription and refill. Read this information carefully each time.
Talk to your childcare team about using this medicine in children. Special care may be required.
Oxycodone, sold under the trade names Roxicodone and OxyContin (extended-release form), among others, is an opioid drug used to treat moderate to severe pain. It is a highly addictive drug and is often abused. It is usually taken orally and is available in both immediate-release and controlled-release formulations. Pain relief usually begins within 15 minutes and lasts up to six hours with an immediate-release formulation. In the UK it is available by injection. Combination medications containing paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin are also available.
Common side effects include euphoria, constipation, nausea, vomiting, loss of appetite, drowsiness, dizziness, itching, dry mouth, and sweating. Serious side effects can include addiction and dependence, irritability, depression or mania, hallucinations, hypoventilation, gastroparesis, and hypotension. People who are allergic to codeine may also be allergic to oxycodone. The use of oxycodone in early pregnancy appears to be relatively safe. Opioid discontinuation can occur with rapid withdrawal. Oxycodone works by activating the -opioid receptors. When taken by mouth, it has about 1.5 times the potency of the equivalent amount of morphine.
Oxycodone was first produced in Germany by Thebain. It is on the World Health Organization's List of Essential Medicines.[19] It is available as a generic. In 2019, it was the 49th most-prescribed drug in the United States with more than 14 million prescriptions. A number of anti-abuse formulations are available, for example in combination with naloxone or naltrexone.
Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient. It may improve quality of life in certain types of pain. It is unclear if use in chronic pain results in improved quality of life or ongoing pain relief.
Oxycodone is available as a controlled-release tablet, intended to be taken every 12 hours. A July 1996 study independent of Purdue Pharma, the drug's originator, found the controlled-release formulation had a variable duration of action ranging from 10 to 12 hours. A 2006 review found that controlled-release oxycodone is comparable to immediate-release oxycodone, morphine, and hydromorphone in management of moderate to severe cancer pain, with fewer side effects than morphine. The author concluded that the controlled-release form is a valid alternative to morphine and a first-line treatment for cancer pain. In 2014, the European Association for Palliative Care recommended oxycodone by mouth as a second-line alternative to morphine by mouth for cancer pain.
In the U.S., extended-release oxycodone is approved for use in children as young as eleven years old. The approved uses are for the relief of cancer pain, trauma pain, or pain due to major surgery, in children already treated with opioids, who can tolerate at least 20 mg per day of oxycodone; this provides an alternative to Duragesic (fentanyl), the only other extended-release opioid analgesic approved for children.
Oxycodone is available as a controlled-release tablet, intended to be taken every 12 hours. A July 1996 study independent of Purdue Pharma, the drug's originator, found the controlled-release formulation had a variable duration of action ranging from 10 to 12 hours. A 2006 review found that controlled-release oxycodone is comparable to immediate-release oxycodone, morphine, and hydromorphone in management of moderate to severe cancer pain, with fewer side effects than morphine. The author concluded that the controlled-release form is a valid alternative to morphine and a first-line treatment for cancer pain. In 2014, the European Association for Palliative Care recommended oxycodone by mouth as a second-line alternative to morphine by mouth for cancer pain.
In the U.S., extended-release oxycodone is approved for use in children as young as eleven years old. The approved uses are for the relief of cancer pain, trauma pain, or pain due to major surgery, in children already treated with opioids, who can tolerate at least 20 mg per day of oxycodone; this provides an alternative to Duragesic (fentanyl), the only other extended-release opioid analgesic approved for children.